Description
Indications
The drug is indicated for the treatment of
- Early-stage invasive breast cancer, whose cells have hormone receptors, in postmenopausal women as adjuvant therapy.
- Early stage invasive breast cancer in postmenopausal women after completion of standard adjuvant therapy with tamoxifen for 5 years as extended adjuvant therapy.
- Common hormone-dependent forms of breast cancer in postmenopausal women (first-line therapy).
- Disseminated forms of breast cancer with disease recurrence or progression in postmenopausal women (natural or induced) who have received prior anti-estrogen therapy.
- Hormone-dependent HER-2 negative breast cancer in postmenopausal women as neoadjuvant therapy when chemotherapy is contraindicated and emergency surgery is not required.
Contraindications
Hypersensitivity to letrozole or any of the other components of the drug.
Endocrine condition specific to the reproductive period.
Pregnancy, lactation period.
Age below 18 years.
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